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Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. Vardenafil is considered five to 10 times more potent than sildenafil. Structurally, vardenafil (38.3.2) is very similar to sildenafil (38.3.1) and differs in that the pyrazolo-pyrimidine heterocycle is replaced by an isosteric imidazo-triazine core. Background and purpose: The type‐5 PDE inhibitor vardenafil reduces myocardial infarct size in situ, following ischemia/reperfusion, when applied at reperfusion in animal models. Little is known ab vardenafil liquid, hearing loss vardenafil, vardenafil data sheet, vardenafil pka value, vardenafil vs sildenafil citrate, staxyn vardenafil hydrochloride, vardenafil hydrochloride, flomax vardenafil, vardenafil paypal, vardenafil n-oxide, pharmacokinetics of vardenafil, vardenafil india, vardenafil tables, vardenafil grapefruit interaction, vardenafil vs cialis, vardenafil in pulmonary Tabletter.

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On increasing the pH from 4 … Vardenafil is a selective, orally active, potent inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows selectivity over PDE1 (180 nM), PDE6 (11 nM), PDE2, PDE3, and PDE4 (>1000 nM). Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil can be used for the research of erectile dysfunction.

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